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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP2
All Species:
26.36
Human Site:
S199
Identified Species:
58
UniProt:
Q13822
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13822
NP_001035181.1
863
98994
S199
L
R
S
C
G
T
H
S
P
Y
M
R
P
V
Y
Chimpanzee
Pan troglodytes
XP_001143143
888
101936
S199
L
R
S
C
G
T
H
S
P
Y
M
R
P
V
Y
Rhesus Macaque
Macaca mulatta
XP_001093656
982
112340
S293
L
R
S
C
G
T
H
S
P
Y
M
R
P
V
Y
Dog
Lupus familis
XP_861274
859
98531
S199
L
R
S
C
G
T
H
S
P
Y
M
R
P
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1E6
862
98867
A198
L
R
S
C
G
T
H
A
P
Y
M
R
P
V
Y
Rat
Rattus norvegicus
Q64610
887
101558
A198
L
R
S
C
G
T
H
A
P
Y
M
R
P
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505967
868
99060
S194
L
K
T
C
G
I
H
S
Q
Y
M
R
A
V
Y
Chicken
Gallus gallus
XP_418466
915
104916
S199
L
R
S
C
G
T
H
S
P
Y
M
R
P
V
Y
Frog
Xenopus laevis
NP_001080526
874
99632
S199
L
R
S
C
G
T
H
S
P
Y
M
R
P
V
Y
Zebra Danio
Brachydanio rerio
NP_956897
850
97175
A194
L
R
S
C
G
T
H
A
P
Y
M
R
P
M
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90754
829
93146
R197
F
A
R
E
Y
V
D
R
N
I
V
Q
T
L
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
86.8
95.3
N.A.
94
91.3
N.A.
45.3
79.3
73.8
66
N.A.
N.A.
N.A.
24.4
N.A.
Protein Similarity:
100
97
87.3
97.6
N.A.
97.2
94.5
N.A.
62.7
86.9
86.5
82.2
N.A.
N.A.
N.A.
41.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
66.6
100
100
86.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
100
100
100
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
28
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
91
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
91
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
91
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
91
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
82
0
0
0
82
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
82
10
0
0
0
0
10
0
0
0
91
0
0
0
% R
% Ser:
0
0
82
0
0
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
82
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
0
0
82
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
91
0
0
0
0
91
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _